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Simultaneous occurrence of hepatic adenoma and focal nodular hyperplasia: report of a case and review of the literature.

Friedman LS, Gang DL, Hedberg SE, Isselbacher KJ.

We report the case of a 28-year-old woman with a history of oral contraceptive use and the simultaneous occurrence of histologically proven hepatic adenoma and focal nodular hyperplasia. A review of the literature discloses that the simultaneous occurrence of these hepatic lesions is a rare event. Epidemiologic evidence suggests that hepatic adenomas are etiologically related to oral contraceptive use, whereas focal nodular hyperplasia does not seem to be caused by these agents. The finding of the two lesions in the same liver may represent the chance occurrence of two rare diseases.

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PMID: 6724520 [PubMed - indexed for MEDLINE]