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Biochemical data. Aspartate-aminotransferase (AST), alanine-aminotransferase (ALT), AST/ALT ratio, ammonia, albumin, thiostatin and α 1 acid glycoprotein (α 1-AGP) serum concentrations in control rats and in rats with portacaval shunt (PCS), 4 weeks after the operation. |
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| Group |
Control (n = 11) |
PCS (n = 11) |
p-value |
|
|
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| AST (IU/L) |
65.72 ± 11.19 |
134.50 ± 67.60 |
p = 0.004 |
| ALT (IU/L) |
29.36 ± 5.90 |
65.33 ± 27.27 |
p = 0.0001 |
| AST/ALT |
2.35 ± 0.08 |
2.38 ± 1.58 |
NS |
| Ammonia (μmol/L) |
104.00 ± 48.05 |
274.00 ± 92.25 |
p = 0.0001 |
| Albumin (g/dl) |
2.89 ± 0.18 |
2.54 ± 0.08 |
p = 0.0001 |
| Thiostatin (mg/ml) |
0.09 ± 0.01 |
0.23 ± 0.04 |
p = 0.001 |
|
Data presented as: Mean ± SD. NS = non-significant difference. | |||
Aller et al. Comparative Hepatology 2008 7:1 doi:10.1186/1476-5926-7-1 |
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