Table 1

Effect of diet reversal on weight, insulin and glucose levels of type 2 diabetic mice.


Weight (g)

Plasma Insulin (ng/ml)

Fasting Glucose (mg/dl)


35.1 (3.5)a

326 (190)a

150 (13.8)a


56.5 (5.3)b

1981 (1170)b

153 (17.9)a


37.1 (1.9)a

247 (104)a

114 (11.4)b

Values are: mean (SD). N = 4 (for each group). Means in a column without a common letter differ significantly, P < 0.05. SC denotes mice fed standard chow; HF denotes mice fed the high fat diet; HF-SC denotes diet-reversed mice that were first fed the high fat diet and switched to standard chow.

Kelder et al. Comparative Hepatology 2007 6:4   doi:10.1186/1476-5926-6-4

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