Figure 7.

Expression of AFP gene and Rev-Erb A, Rev-Erb B and N-CoR during acute phase reaction. After turpentine oil treatment, the expression of AFP gene (A) and of Rev-Erb A, Rev-Erb B and N-CoR (B) were measured by real-time PCR in the rat liver. The mean values of the two different series are demonstrated in this Figure. In this model, only a slight up regulation of the AFP gene expression could be observed at 48 h. The strongest down regulation of Rev-Erb A occurs at 2, 24 and 36 hours. Compared to Rev-Erb A, Rev-Erb B gene expression was not significantly altered, e.g., decreased maximally by 4.5 fold at 24 hours.