Figure 6.

Expression of AFP gene and Rev-Erb A, Rev-Erb B and N-CoR in fetal rat liver. The expression of the AFP gene (A) and of Rev-Erb A, Rev-Erb B and N-CoR (B) were measured by real-time PCR in the fetal rat liver. The full-length AFP-RNA reach the maximum at day 14 (21,500 fold); afterwards, a continuous decrease up to day 18 could be observed. Rev-Erb A and Rev-Erb B are down regulated at each time point, the maximum down regulation could be seen after 12 days. N-CoR was slightly down regulated at each time point (about 1.5 fold).