Figure 6.

Western blot analysis of liver homogenates of controls, CPSS, and PPVH. Detection of HGF, c-MET, PKB, STAT, and ERK shown in (A), detection of the TGF-β1, Smad2, and Collagen I in (B), and detection of the Caspase-3protein, uncleaved/inactive 34 kDa, and cleaved/active products of 20 kDa and 13 kDa in (C). Western blot analysis of liver homogenates (n = 6 dogs per group, randomly chosen from original group). Lane samples: 1 = control; 2 = congenital portosystemic shunt; 3 = primary portal vein hypoplasia.