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Resolution: standard / high Figure 5.
Non-competitive inhibition of CYP1A by ethynylestradiol (A) and uncompetitive inhibition of CYP3A by ethynylestradiol (B). Dixon plots for ethynylestradiol on A) EROD activity (diamonds represent 8.2; squares represent 25 and triangles represents 677 pM ethoxyresorufin). B) BFCOD activity (diamonds represent 200; squares represent 267 and triangles represents 356 μM BFC).
Hasselberg et al. Comparative Hepatology 2005 4:2 doi:10.1186/1476-5926-4-2 |