|
Values {Area under the ROC curves (AUROCs)} of SteatoTest, GGT and ALT for the diagnosis of steatosis greater than 5%, in both training and validation groups. |
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| Diagnostic panel |
Training Group AUROC (se) |
Validation Group 1 – HCV before treatment |
Validation Group 2 – HCV sustained responders |
Validation Group 3 – Alcoholic liver disease |
All groups |
|
|
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| N = 310 |
N = 171 |
N = 201 |
N = 62 |
N = 884 |
|
| SteatoTest |
0.79 (0.03)* |
0.80 (0.04)£ |
0.86 (0.03) $ |
0.72 (0.05)** |
0.80 (0.02) ££ |
| GGT |
0.66 (0.03) |
0.67 (0.05) |
0.74 (0.05) |
0.50 (0.09) |
0.66 (0.02) |
| ALT |
0.58 (0.03) |
0.62 (0.05) |
0.79 (0.04) |
0.66 (0.07) |
0.61 (0.02) |
|
* – Higher than GGT (P < 0.0001) and ALT (P < 0.0001); £ – Higher than GGT (P = 0.007) and ALT (P < 0.0001); $ – Higher than GGT (P = 0.02); ** – Higher than GGT (P = 0.002); ££ Higher than GGT (P < 0.0001) and ALT (P < 0.0001). | |||||
Poynard et al. Comparative Hepatology 2005 4:10 doi:10.1186/1476-5926-4-10 |
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