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The effect of portal venous flow (PVF) reduction on hepatic arterial flow (HAF) and mean arterial blood pressure (MAP). |
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| BEFORE PORTAL VENOUS OCCLUSION |
AFTER PORTAL VENOUS OCCLUSION |
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| Exp. no. |
n |
HAF (ml. min-1.100 g-1) |
PVF (ml. min-1.100 g-1) |
MAP (mmHg) |
HAF (ml. min-1.100 g-1) |
PVF (ml. min-1.100 g-1) |
MAP (mmHg) |
HAF increase (%) |
Buffering capacity (%) |
|
|
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| 1 |
4 |
16.9 |
143.2 |
95.0 |
25.3 |
39.1 |
96.8 |
66.8 |
8.9 |
| 2 |
2 |
17.5 |
64.2 |
67.5 |
22.5 |
35.0 |
72.5 |
28.5 |
17.6 |
| 3 |
2 |
9.4 |
63.5 |
70.0 |
11.4 |
48.5 |
75.0 |
22.0 |
15.1 |
| 4 |
6 |
25.4 |
70.9 |
75.0 |
36.7 |
31.5 |
84.2 |
40.3 |
33.2 |
| 5 |
3 |
27.8 |
- |
93.3 |
32.1 |
- |
97.3 |
15.3 |
- |
| Mean (SE) |
- |
19.4 (3.3) |
85.5 (19.3)* |
80.2 (5.8)* |
25.6 (4.3) |
38.5 (3.7) |
85.2 (5.2) |
34.6 (9.1) |
18.7 (5.2) |
|
Each value is the mean of the number of observations stated. Both HAF and MAP increased significantly during PV occlusion (* p < 0.05, n = 5). | |||||||||
Browse et al. Comparative Hepatology 2003 2:9 doi:10.1186/1476-5926-2-9 |
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