Table 2

Percentage of necrosis and apoptosis in hepatocytes isolated from control, KNO3, GdCl3 and Pb(C2H3O2)2 treated animals.*


Control
KNO3
GdCl3
Pb(C2H3O2)2

%

1 day
3 days
5 days
1 day
3 days
5 days
1 day
3 days
5 days

Necrosis
5 (1.2)
7 (2.1)
18^(2.1)
45^(1.6)
15^(2.7)
16^(3.2)
20^(3.5)
6 (1.6)
7 (2.8)
10 (1.8)
Apoptosis
2 (0.2)
1 (0.2)
17^(3.4)
15^(1.0)
2 (0.9)
10 (2.3)
12^(4.1)
1 (0.1)
12 (2.8)
41^(7.5)

* Values are given as mean (standard deviation), of at least three independent experiments of flow cytometry analysis. For each value, at least 10 000 events were counted. ^Significantly different in relation to Control (p < 0.05).

Pagliara et al. Comparative Hepatology 2003 2:8   doi:10.1186/1476-5926-2-8