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Structural and functional aspects of liver sinusoidal endothelial cell fenestrae: a review

Filip Braet email and Eddie Wisse email

Laboratory for Cell Biology and Histology, Free University of Brussels (VUB), Laarbeeklaan 103, 1090 Brussels-Jette, Belgium

author email corresponding author email

Comparative Hepatology 2002, 1:1doi:10.1186/1476-5926-1-1

Published: 23 August 2002

Abstract

This review provides a detailed overview of the current state of knowledge about the ultrastructure and dynamics of liver sinusoidal endothelial fenestrae. Various aspects of liver sinusoidal endothelial fenestrae regarding their structure, origin, species specificity, dynamics and formation will be explored. In addition, the role of liver sinusoidal endothelial fenestrae in relation to lipoprotein metabolism, fibrosis and cancer will be approached.


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